Tuesday, October 8, 2013

BUSTED! Innovative Electrostatic Spray Ionization Method Detects Fake Perfumes


Scientists at EPFL have designed a quick method for detecting counterfeit perfumes, and have tested it on major brands like Givenchy, Hermes and D&G.

Counterfeit perfumes are costing the cosmetic industry and consumers significant amounts of money. But identifying imitation perfumes can be a difficult and time-consuming task despite a number of available analytical techniques. Publishing in Rapid Communications in Mass Spectrometry, EPFL researchers have developed an innovative method called Electrostatic Spray Ionization that can analyze and identify counterfeit perfumes faster than conventional methods.

Six fragrances from well-known manufacturers including Givenchy, Hermes and D&G were tested by the team of Hubert Girault at EPFL using their novel detection method (ESTASI). The commercial fragrances were analyzed and compared to a ‘model’ perfume made up of ten different compounds. The results showed that the new method was able to quickly distinguish between authentic perfumes and their ‘model’ counterfeit. Because there is no need for time-consuming preparations of the samples before testing, the new method provides a rapid, high-throughput means of fingerprinting and identifying perfumes.

The first, and often most challenging step to analyzing a chemical is to ionize it; that is, to break it up into smaller pieces that carry an electrical charge. This is usually done by turning these fragment ions into a fine spray, which is why this process is called “electrospray ionization”. The ions are then analyzed by a detector that records the electrical charge of each passing ion. The result is a ‘fingerprint’ pattern that is unique to the tested sample and can be compared to fingerprints of other samples. This makes it possible to determine the elements that make up almost any chemical, including proteins or other complex compound.

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